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Compound of Fitokimia which implied in leaf of Piper Betle Linn namely alkoloid, saponin, tanin, and flavonoid. According to Ivorra, M.D in book of A Potential Review Natural Product Plants ace and of Antidiabetic, active compound and alkoloid of flavonoid have activity of hipoglikemik or penurun of blood glucose rate. Young researcher of Institute Agriculture Of Bogor ( IPB), Mega of Safithri and of Farah Fahma have checked extract security irrigate red leaf and its ability in degrading blood glucose rate. Making of leaf extract of Piper Betle Linn very easy. Counted 200 leaf gram of Piper Betle Linn braised with 1 litre irrigate until its volume remain 100 ml. Heavy comparison leaf of Piper Betle Linn with extract volume of cookery the drinked is 200 g : 100 ml or 2 : 1. For knowing security storey;level and leaf side effects having the character of this antiseptic, Mega test toksisitas. Extract with concentration 0, 5, 10, 20 g / body wight singk given by oral at each six mouse tail of Sparague dawley. Although its examination use mouse, however application can at human being patient of Diabetes Militus. Its dose patient body weight multiplied by 20g / singk of BB,” clear [of] Departmental Staff Instructor of Bichemistry Faculty Mathematics and Natural Sciences of IPB this. He/She suggest, if patient of DEUTSCHMARK have body weight 50 singk hence he require 1 leaf singk of sirih fresh red or 500 extract ml irrigate rebusan. This Ektrak can be drinked twice sehari each;every evening and morning counted 250 ml. Still, test direct klinis at patient of diabetes have never been [done/conducted].
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